Apple on Monday released the first look at the series, which is set to debut this fall.
No actual footage of the stars in action is shown in the minute-long sneak peek, but moody shots of hallways set the tone for the preview.
The overlapping voices of Witherspoon, Carell and Aniston are also heard in a cacophony of dramatic moments.
“I’m a journalist, I can feel when the world needs me,” Carell can be heard saying at one point.
“People want to trust that the person telling them the news of the world is an honest person,” Witherspoon’s character says at another.
The show, Witherspoon said at the event, pulls back “the curtain on “the power dynamics between men and women in the high-stakes world of morning news shows.”
“It’s a real insiders view into the lives of the people who help America wake up every day,” she added.